Within-host evolutionary dynamics of antimicrobial quantitative resistance
نویسندگان
چکیده
10 Antimicrobial efficacy is traditionally described by a single value, the minimal inhibitory concentration (MIC), which lowest that prevents visible growth of bacterial population. As consequence, bacteria are classically qualitatively categorized as resistant if therapeutic concentrations below MIC and susceptible otherwise. However, there continuity in space resistance levels. Here, we introduce model within-host evolution
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ژورنال
عنوان ژورنال: Mathematical Modelling of Natural Phenomena
سال: 2023
ISSN: ['1760-6101', '0973-5348']
DOI: https://doi.org/10.1051/mmnp/2023019